Aquatic animal tumor model
Aquatic animal tumor models are an important tool for cancer research, helping to understand tumor biology, drug efficacy, and disease progression.
Aquatic Animals as Tumor Models
Aquatic animal tumor models use marine species' unique physiological and genetic characteristics to study tumor occurrence and development. They also present ethical advantages over mammalian models, allowing in vivo studies with reduced regulatory burdens. In addition, these models enable researchers to conduct longitudinal studies of cancer evolution and therapy response, leading to a deeper understanding of tumor heterogeneity.
| Species | Advantages | Applications |
| Zebrafish (Danio rerio) |
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| Medaka (Oryzias latipes) |
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Preclinical Validation
Evaluate the efficacy of drug candidates in aquatic animal tumor models, conduct mechanism studies, elucidate the molecular mechanisms of drug action, and gain insight into how drugs affect tumor cells and the surrounding microenvironment.